4-5 June 2015, Vejle (Denmark) hosted an international scientific conference “Stem Cells and Tissue Engineering”, organized with the support of the Danish Stem Cell Society and the Danish Biotechnological Society.
Conference “Stem Cells and Tissue Engineering” (2015) included the following thematic sections:
1. Cloning and reprogramming
2. Stem cells in the treatment of diabetes
3. Production, banking and upscaling of stem cells for disease modelling
4. Ethics in stem cell research
5. Bioengineering and transplantation
6. Tissue engineering and organ design
7. Regenerative medicine
Themes of the conference “Stem Cells and Tissue Engineering” shows increased attention of modern scientists to the study of induced pluripotent stem cells, which hold great promise of bioengineering, treatment of a number of serious diseases, modeling of diseases in the experiment. For the discovery of induced pluripotent stem cells in 2012, researchers John Gurdon and Shinya Yamanaka were awarded the Nobel Prize. We recall that cord blood cells are considered the most promising biomaterial to obtain stem cells with induced pluripotency.
The author Xianmin Zeng of California (USA) presented the results of research on the dopaminergic neurons from pluripotent stem cells for potential use in the treatment of Parkinson’s disease.
Dr. Timothy Allsopp from the research division of the company «Pfizer» presented the project of the European Bank for pluripotent stem cells, for the discovery of which in 2012, researchers John B.Gurdon and Shinya Yamanaka were awarded the Nobel Prize. Induced pluripotent stem cells are promising from the point of view of treating various diseases and tissue engineering, as well as for modeling of disease in the experiment.
Dr. Kim Jensen from the University of Copenhagen (Denmark) considered the role of progenitor cells from the epithelium of the small intestine in the development of cancer and possible ways to control the behavior of these cells.
Researchers from London University College and the Institute of Ophthalmology (UK) discussed new methods of treatment of age-related macular degeneration of the retina based on the use of stem cells.
Dr. Ulrich Martin (Germany) presented the approaches to the use of induced pluripotent stem cells in cardiology and expressed the hope that in the coming few years these pioneering treatments will be introduced into clinical practice.
Dr. Petter Björquist from «NovoHep AB» presented an interesting paper “Stem cell bio-engineering and individualisation of human organs – applications in regenerative medicine and toxicity testing” So, the scientists proposed a new organ bioengineering technology, which is based on seeding of patient’s own stem cells on a decellularised donor matrix, which allows to turn allogenic tissue into autologous. This method solves two problems – to get donor biomaterial and eliminate the need for immunosuppression after transplantation. The developed technology opens up the possibility of creating tissue-engineered organs such as kidneys, liver, pancreas, blood vessels. Researchers are preparing for the first phase of clinical trials of tissue-engineered veins.
A team of scientists from Denmark, Switzerland and Germany presented the technology of creating of 3D-models of the pancreas for potential use in the treatment of diabetes.