The application of cell therapy in the treatment of inflammatory bowel disease currently is of increasing scientific interest. Cell therapy in the treatment of Crohn’s disease and ulcerative colitis includes 2 approaches: immunosuppressant followed by hematopoietic stem cells transplantation and systemic or local application of mesenchymal stem cells.
The latter were reported to exhibit immunosuppressive and regenerative effect. Actually more than 1,500 patients with inflammatory bowel disease have been treated with mesenchymal stem cells worldwide. The introduction of cell therapy into gastroenterology will significantly expand the arsenal of therapeutic arrangements for the treatment of inflammatory bowel disease, in particular resistant forms of the disease and will allow to increase the effectiveness of treatment.